Association analysis module provides many different family-based association tests between trait(s) and both single-variant (common variant) and gene-based (rare variant).

Single variant

Summary of single variant analyses available in ONETOOL:

../_images/assoc_1.JPG

Gene-based (Rare variant)

Summary of gene-based (rare variant) analyses available in ONETOOL:

../_images/assoc_2.JPG

Dosage/genotype probability data

ONETOOL can take the dosage and genotype probability files from several popular imputation tools available for population data.